skwoodwiva wrote:So you take all your IR niacin at one time per day?
Hmmm, I spread my 7 gr out with my AA doses. Yet I did have this recent liver rebellion & pain. I went off it for a week. Now I am good(liver stats too) but a single dose per day may reduce the risk of this strange reaction....
The important part is to start low dose and go slow for avoiding a too unpleasant flush. Since it really is important to like to take your supplements in the long run. Within time your at the required dose. Mostly I took upto 3.5 g niacin per daily dose. Because the flush with slowly titrating becomes very soon unnoticeable, I started to miss the warmth and tingling, therefore at one point even took up to 7 g every second day to get it back (because I read every other day would work just as well with half that dose - though didn't make a difference in my case).
However, at the beginning I too had a very unpleasant flush with 150 mg only. That is 9 years ago. But again, don't use sustained release at higher doses at all, to not harm your liver.