There are several ways to determine the optimal vitamin C, and lysine intake, for CVD in general.
Knowing your bowel tolerance, or Jaffee C Calibration number, gives you a current ball park of vitamin C dosage to shoot for. The normal population can metabolize from 4000 to 20000 mg of vitamin C daily. For people who can take more, there is probably some kind of toxicity or other stress issue that is causing an increased requirement for vitamin C. If you can tolerate 30,000 mg, or even 60,000 mg of vitamin C without loose stools, then if it were me, I would take that much until whatever is causing the stress is resolved.
Lysine should match vitamin C to about 6000 mg (6 g) but in our experience, little more is required for the anti-CVD effect. It is the amount of vitamin C that seems to vary so much between individuals.
Thanks Owen, right now I've been averaging 15 to 20 grams of C per day. I got some Lipsomal as well and will take 9 grams of that perday in addition. And have some lysine proline capsules that I take as well. I also take ypur cardio-c 2 scoops per day.