Vitamin C Forum

zarfas wrote:

Lone Dog wrote:I was surprised to see this in a national newspaper, but it's interesting.

http://www.dailymail.co.uk/health/artic ... tacks.html

the article seems very wrong
no where did I see LPA=surrogate for collagen nor vit C
nor lysine/proline niacin, etc


Could pumping your BLOOD through a machine help prevent heart attacks? Scientists believe they've found protein that causes heart disease

Patients are told to reduce cholesterol to lower risk of heart disease and stroke
However scientists now believe the picture is far more complex than that
Study after study points to lipoprotein(a), a fatty particle found in the blood
'Bad' lipoproteins are thought to attach to cholesterol and keep it inside the body

Unlike LDL and HDL cholesterol, the exact role for Lp(a) isn't yet clear, and its levels are not picked up in routine blood tests.

But studies are suggesting that as levels of it rise, so do the risks of cardiovascular disease.

I am pretty sure that the drug is called Inclisiran.

Inclisiran achieves LDL lowering of a magnitude similar to that of the PCSK9-inhibiting monoclonal antibodies alirocumab (Praluent) and evolocumab (Repatha), but it will be less expensive to produce and far less costly to administer than the monoclonal antibodies. Dosing is planned to be two or three injections per year, rather than every 2 or 4 weeks, as with the PCSK9 inhibitor monoclonal antibodies, which cost a hefty $14,000 per year. And the sustained efficacy of a dose of inclisiran should make patient adherence to LDL-lowering therapy less of an issue, Dr. Ray continued.