momom wrote:I'm looking for info regarding high doses of vitamin C and other vitamin or mineral deficiencies/imbalances. I don't want to start a new thread on this topic if one has already been started so if this has already been discussed could somebody tell me where to find it on the forum? If this is a new topic I would appreciate thoughts and ideas on this topic.
Owen wrote:Think about the majority of mammals, or almost all species for that matter, that produce endogenous vitamin C, 24 hours a day, seven days a week
Mineral changes can and will happen with some/all people regarding vitamin C megadoses.
So say you, and many others over the Internet, without much evidence. Vitamin C is the second most studied substance in the history of science (according to Pauling in 1971). If Pauling didn't spot the problem, I doubt very much whether it really exists.
Following Linus Pauling's regimen in HTLLAFB will make the issue moot in probably 90% of the population - no matter what you eat
But if you are proposing some "effect" caused by vitamin C - after digestion - then you have to explain why the same effect doesn't occur in all animals.
majkinetor wrote:There is much evidence. This is even not controversial, that C will reduce copper status.
Intake of high dietary iron (10 times control) increased hepatic iron stores and produced a reciprocal decrease in hepatic copper. Even though splenic iron increased, no significant change in copper resulted.
Pharmacologic doses (25 mg per 100 g BW per day) of vitamin C resulted in two-to-three-fold decreases in liver copper, when compared with those receiving normal (0.5 mg per 100 g BW per day) intakes. Under conditions of vitamin C deficiency, serum copper and ceruloplasmin were elevated along with liver copper.
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