We do have one report of a fellow in Wisconsin who took the Heart Technology product with fiber - without significant results. He then began avoiding taking the vitamin C/lysine with fiber, and many of his symptoms/lab results got better.
As a general rule, taking vitamin C/lysine with carbs is probably not optimum, but taking with protein probably is better.
I know that after experimentation, people report that generally, taking vitamin C/lysine in large doses about 20 minutes prior to the meal minimizes gastric symptoms.
If you can tolerate taking vitamin C/lysine "alone" this is obviously a good way to assure it is most bio-available.
Owen R. Fonorow, Follow #OWENRFONOROW at twitter