Yes, splitting the dosage should reduce GI side effects.
According to Hickey/Roberts as described in their book ASCORBATE: THE SCIENCE OF VITAMIN C (lulu.com/ascorbate) the half life of vitamin C in the blood is 30 minutes, and the amount to keep blood levels consistently at their highest is 500 mg every 3 to 4 hours. (For me, this is not convenient so I tend to take my 9000 mg twice per day.)
Getting off drugs is always a plus.
I have noticed that the benefits far outweigh any disadvantage, (judging from the shortage at Livon.) If you take it the proper way - there is NO taste. Tear the Lypo-GSH packet, and drop the contents into a glass filled with just the amount of water or juice you can swallow in one gulp.
Owen R. Fonorow, Follow #OWENRFONOROW at twitter