Does splitting the dosage reduce GI side effects?

This forum will focus on the interesting topic of titrating oral vitamin C intake to so-called bowel tolerance, the point just prior to the onset of diarrhea

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Does splitting the dosage reduce GI side effects?

Post Number:#1  Post by poisade1 » Fri May 11, 2012 8:17 am

I got your message Owen and forwarded it to my friend. I, as I may have mentioned was taking 5gms./day all at once. I started to have some GI effects, so I cut back to 4gms. I no longer need the Prozac, and have cut way back on the Ritalin as well as the Xanax. Could I avoid the GI effects and go back up to 5 gms/day by splitting the dosage times?

Also, I beleive I could benefit greatly by adding the GSH, but reading in the literature that it has a 'rotten egg' taste due to the sulfur component-I just don't think I could get it down without gagging. That is, unless I could swallow something immediately after to remove the aftertaste. Would doing that effect its efficacy? If so, I'm going to have to search out a B Complex from somewhere else that is just as bio-available as GSH, but in capsule form. Any thoughts?


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Re: Does splitting the dosage reduce GI side effects?

Post Number:#2  Post by ofonorow » Tue May 15, 2012 3:33 am

Yes, splitting the dosage should reduce GI side effects.

According to Hickey/Roberts as described in their book ASCORBATE: THE SCIENCE OF VITAMIN C ( the half life of vitamin C in the blood is 30 minutes, and the amount to keep blood levels consistently at their highest is 500 mg every 3 to 4 hours. (For me, this is not convenient so I tend to take my 9000 mg twice per day.)

Getting off drugs is always a plus.

I have noticed that the benefits far outweigh any disadvantage, (judging from the shortage at Livon.) If you take it the proper way - there is NO taste. Tear the Lypo-GSH packet, and drop the contents into a glass filled with just the amount of water or juice you can swallow in one gulp.

Owen R. Fonorow, Orthomolecular Naturopath
My statements have not been evaluated by the Food and Drug Administration. Any product mentioned is not intended to diagnose, treat, cure or prevent any disease.”

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Re: Does splitting the dosage reduce GI side effects?

Post Number:#3  Post by CeeCee101 » Mon Jan 11, 2016 12:37 pm

Personally, I have found to have less GI distress when taking sodium ascorbate every 4 hours instead of every 2 hours, with the same dosage in total.

It could be, because when taking it every 2 hours, it's bound to be taken on a full stomach sometimes. When I take it on a full stomach I get bloated and gassy.

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