New Method for Very High Potency Liposomal Vitamin C

Discussion of the benefits and disadvantages of commercial and homemade (DIY) liposomal vitamin C

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Kina
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Thu Jul 12, 2018 7:46 am


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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Fri Jul 13, 2018 12:49 am

If you want to check the pH of a solution I think the cheaper way would be go to the local chemist and buy a pack of Multistix SG10 which contains 100 strips - which include the pH test color coding each pH. They are about $50AUD.

Supposed to be used for urine but would generally work for any solution. i Just used it to test the pH of a weak solution of Ascorbic Acid which came in at least 5 or more acidic.

https://www.healthcare.siemens.com.au/u ... s-benefits

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Fri Jul 13, 2018 12:56 am

With regard to the method of making DHA using zuccini.

The test solution for residual ascorbic acid, in the green smoothie, is 2% iodine solution with corn starch.
Unfortunately I can't get that, best was 5% iodine, but it was mixed with another chemical, and it fails to test sensitively for acid.
I tried using Bi-Carb power with a drop of weak Ascorbic Acid - but is difficult to ascertain, and not sensitive enough.
I wouldn't be able to use the multistix SG10 because of the green food color of the solution.

LATER
I have revisited the Corn Starch Iodine solution method of testing residual Ascorbic Acid in solution - adjusted the ratios to take account of the additional ingredient in my iodine bottle, and now got it to work.

I thus made a small solution of Ascorbic Acid in water.
And progressively tested with the Iodine, diluting the AA each time - to gauge how sensitive the iodine solution was (and tasting the AA solution each time to know how 'strong').

I got to the state of AA dilution where I could barely taste the AA, but it was still registering somewhat in the Iodine test solution.

Need to take care that your drop of AA into the drop of Iodine solution is actually removing color, not just diluting the Iodine color.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Sat Jul 14, 2018 10:07 am

I mentioned before that I had two batches that were acidic - so in the end put them together and heated them to a higher heat - and got on cooling a palatable much less acidic thick solution.

This seems to be a valid process. And I have applied to a batch that was good, but the liposomes started to degrade and solution become more acidic - so reheated quickly to higher temp - possibly 70-80C

Reheating the Lecithin past its transition temperature (and I think we need to go clearly past this temp) will not harm the Ascorbic Acid too much if you do this in less than 15 minutes.

Research of heat on VC - that included a control of an Asocrbic Acid solution - showed at temperatures of 70c 80c and 90c less then 15 minutes of exposure resulted in a small loss. AND i think in a Lecithin solution the loss would be much less, since there would be less oxidation than in pure water.

This study includes a AA in solution control - which shows the result of heat on it.
https://pdfs.semanticscholar.org/aaf2/a ... 2a949f.pdf

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Mon Jul 16, 2018 7:30 pm


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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Wed Jul 18, 2018 8:06 am


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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kina » Wed Jul 18, 2018 8:50 am

While I'm thinking of it Dr Mercola Liposomal Vitamin C - is NOT liposomal.
LivOn labs rips it apart.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jara_j » Fri Jul 27, 2018 2:46 am

There are alvays doubt about encapsulation of home made LVC. If you make LVC with Ascorbic Acid, you can easy test encapsulation by this method. You only need precision scales, sodium bicarbonate and pH meter (or pH stick).

1. Pour out sample of LVC about 10g, record the exact weight (W1).
2 Add deistilled water about 50g, record exact weight of added water (W2).
3. Gently mix and then let Liposoms go down. Pour out water with dissolved non liposomal AA into another glass. You can easily separate up to 90% of it from liposomes. Record weight of separated solution (W3).
4. Measure pH of separated solution and in small steps add sodium bicarbonate and well mix. Wait until it dissolves. Do until pH goes over 7. Record weight of added sodium bicarbonate (W4).
5. Count amount of non encapsulated AA as W=2.1*W4*W2/W3. Count encapsulation as 1-W/(W1*original percentage of AA/100).

Mine homemade LVC gets result about 50% or more. Batch I made Yesterday get 65%. Theoretical geometrical maximum is 74%.
My Zesterday data:
W1=8.1g, W2=39.4g, W3=35.8g, W4=0.222g, percentage of AA in LVC is 17.9%.

Simnple method so why don't use it to check our products?

Note: You have to separate liposomes out, because they would be destroyed by sodium bicarbonate crystals and all will fail.
Jaromir
Last edited by jara_j on Wed Aug 08, 2018 4:43 am, edited 1 time in total.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jeff » Sat Aug 04, 2018 10:50 am

Greetings. I am new here and have been experimenting with the Quality Liposomal formula. I see a discrepancy between that formula and the Livon patent that would seem to reduce the number of liposomes.

Specifically, the lipid used in the Livon Livon formula contains 50% phosphatidylcholine. So the 18.73% in the formula equates to 9.4% PC total. On the other hand, the lipid used in the Quality Liposomal formula contains only 22% phosphatidylcholine. So, the 20.7% used in the Quality Liposomal formula contains only 4.6% PC. As a result, using only 4.6% PC would seem create far fewer liposomes than the Livon formula.

Does anyone have any thoughts on this?

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by BrightSideOfLife » Sat Aug 04, 2018 1:24 pm

The PC that Livon uses is a purified form whereas this thread uses lecithin and soya lecithin has around 22% PC. The purified PC is very expensive stuff. If you are prepared to purchase a pure form of PC then you can do so. Be aware that the other constituents of lecithin can also have an effect on encapsulation.

Compromises have to be made to make it more affordable.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jeff » Sun Aug 05, 2018 2:00 am

Thank you for your reply. I appreciate that the other components of lecithin may contribute to encapsulation. Putting that aside for the moment, can you think of any reason not to increase the amount of lecithin to approximate the 9.4% PC in the Livon formula (f the mixture becomes too thick, just add water, right?)

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by BrightSideOfLife » Sun Aug 05, 2018 5:51 pm

jara_j wrote:There are alvays doubt about encapsulation of home made LVC. If you make LVC with Ascorbic Acid, you can easy test encapsulation by this method. You only need precision scales, sodium bicarbonate and pH meter (or pH stick).

1. Pour out sample of LVC about 10g, record the exact weight (W1).
2 Add deistilled water about 50g, record exact weight of added water (W2).
3. Gently mix and then let Liposoms go down. Pour out water with dissolved non liposomal AA into another glass. You can easily separate up to 90% of it from liposomes. Record weight of separated solution (W3).
4. Measure pH of separated solution and in small steps add sodium bicarbonate and well mix. Wait until it dissolves. Do until pH goes over 7. Record weight of added sodium bicarbonate (W4).
5. Count amount of non encapsulated AA as W=2,1*W4*W2/W3. Count encapsulation as 1-W/(W1*original percentage of AA/100).

Mine homemade LVC gets result about 50% or more. Batch I made Yesterday get 65%. Theoretical geometrical maximum is 74%.
My Zesterday data:
W1=8.1g, W2=39.4g, W3=35.8g, W4=0.222g, percentage of AA in LVC is 17.9%.

Simnple method so why don't use it to check our products?

Note: You have to separate liposomes out, because they would be destroyed by sodium bicarbonate crystals and all will fail.
Jaromir

I have used your figures and cannot get the encapsulation that you say you accomplished for the provided data.
Encapsulation comes out as 0.33582974899829346735914362809071 and none encapsulated AA (W) gives me 0.51308044692737430167597765363128 this is assuming that the 2,1 is 2.1

Is there an error somewhere? I have calculated it many times but get no where close to 65 (%).

This would need to work correctly before anyone is going to use it.

jeff wrote:Thank you for your reply. I appreciate that the other components of lecithin may contribute to encapsulation. Putting that aside for the moment, can you think of any reason not to increase the amount of lecithin to approximate the 9.4% PC in the Livon formula (f the mixture becomes too thick, just add water, right?)


I cannot think of any reason not to increase the amount of lecithin. I do not use soya lecithin so need to add more to compensate anyway because the lecithin that I use has a lower PC level. Maybe decrease the ascorbic acid and increase the lecithin.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jara_j » Wed Aug 08, 2018 4:40 am

BrightSideOfLife wrote:I have used your figures and cannot get the encapsulation that you say you accomplished for the provided data.
Encapsulation comes out as 0.33582974899829346735914362809071 and none encapsulated AA (W) gives me 0.51308044692737430167597765363128 this is assuming that the 2,1 is 2.1

Is there an error somewhere? I have calculated it many times but get no where close to 65 (%).

This would need to work correctly before anyone is going to use it.



Non encapsulated 0.51 g is right. Total amount of AA is 8.1*0.179=1.45g. Encapsulation 1- (0.51/1.45)=0,65 this is 65%

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by SorinC » Mon Aug 13, 2018 9:33 am

Hi to everyone on this forum ! I'm a new member on this forum and a very beginner in LipVitC subject. Just purchased all the ingredients and tools needed to make some LipVitC but still in research of which method to apply. English is not my first language but I will do my best.
As I said, at the moment, I'm still undecided (probably like most of you around here) which method seems to be more promising in liposomes creation. That's why I am here on this forum, trying, like all of you to find out the answer. In my "research " I came across with this 2 videos:
https://youtu.be/SAV4UlNr19I
https://youtu.be/gRx3BB0KCHg

Following the discussions on this forum, I can easily tell, by far, I'm not the smartest person here, regarding this topic(liposomes and LipVitC).
I'm not a lazy person, I really like to do my research, but as I said above, I do think , many of you might have better understanding if this videos can help all of us in this topic. Probably if any info from this videos might be useful for us, someone can "translate it" and adapt it to our subject.

Another question I want to ask all of you, is, if any of you came across with those " studies/articles " regarding the increased risk of cancer(especially prostate cancer ) on high choline consumption??
On his "welcoming on the forum" e-mail, Owen told me: " ... choline has so many health benefits, I suspect the "cancer risk" is a false story/study designed to scare people away from this important nutrient."
Like all of you, I'm trying to make LipVitC to improve my family's and my own health, not to make it worse.
Is there any of you who might have any information about this "studies" ? Real or false stories???
Thank you very much for understanding!!!
Sorin

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by donw146 » Mon Apr 13, 2020 2:07 pm



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