New Method for Very High Potency Liposomal Vitamin C

[skwoodwiva]

...

That is a Great proposal, ChristopheG.
Might you want add a base line in there too, using a standardized lipo like LivOn or the like?

all for now...

[skwoodwiva]

....

Being an HVAC serviceman, I advise caution using an IR meter on liquid. The emissivity of the surface is key, I think. I use a Cooper probe.
Or you may have double checked with a probe? Newer IRs may have improved, Mine is years old.

[skwoodwiva]

I have tried to attach some photos, but I didn't succeed, or I haven't understood the procedure explained here in the forum.
How is it done?

It is tough, I presume.
I take a pic on my android, up it to Mega (app, you must create an account) then copy the link with key. Just paste the link to your post as I did above.

[skwoodwiva]

Success!
I made an acceptable batch. I do not have any litmus left, but it tastes near to neutral.
I nixed the blender. N2 is still on hand as needed.
I tried Norma's recipe several times and I would see it trying to gel but always went flat and SOUR!!

I modified Norma's recipe:
30 g Now soya L
40 g Rum 40%
70 g Water
soaked 4 hr
raised to 49*C for ~ 10 min

2nd step
20 g Vit C (cassava based, I am an O! I never realized how bad corn based (LivOn) made me feel until now. I know that type A people do tolerate corn)
50 g water
Kept at 36*C but only ~ 2 min prior to,
pulling step 1 @45*C and dribbling step 2 into 1, stiring & etc, in a very chilly kitchen.
It gelled up nicely. I stored in fridg (HVACR guys have cold (35* F) fridg's). Then went shopping for the sonicator. I found a Harbor Freight 35 W baby. It needed lots of modding to work right.

The short 3 min duty cycle needed fixing: wimpy heat sinks, trashing the body, shorting the relay so the power plug is my power switch, among other things...(PM me for NON UL Mods). It works now for hours straight.
It went in the sonicator pan, naked, like some fab pudding all shiny.
So after blasting it for 45 min (in my fridg) the pudding went flat! It never went over 25*C, incl stiring.
It still had some body and the Ph did not change.

For dosing I just add all masses and divide by 20. I have a $20 250g 10mg resolution scale I bought at a Pot shop.

Edit,
If I never cool the batch the PH rises and thickens in 24 hrs.
If I keep it at 35* F it drops and thins out.

Thanks to Everybody and especially Norma

[Cdizzle]

thanks for the write-up!
So I'm assuming you store the mixture at room temperature? Does it spoil after a week or two?

[skwoodwiva]

thanks for the write-up!
So I'm assuming you store the mixture at room temperature? Does it spoil after a week or two?

I have just this week got to a consistent dosingng of about 12 grams a day, so about 3+ days for a double batch.

[karusel]

[efalconi]

Hi guys,

When you are already sonicating the lipo c, is it okay to submerge only half
of the beaker or do we have to fully submerge up to the level of the solution
on the beaker? I ask this because the big and deeper sonicator is a bit expensive.

Best,

Edwin

[karusel]

It's okay to do that but understand that there will be less of the sonicating effect. Larger sonicator usually means higher ultrasonic power, I feel that mine with 2l capacity and 80W power is just strong enough. So I suggest you don't go lower than that. You could use the sonicator's container to irradiate the mixture to a greater effect than if you have it in a beaker sitting in a water bath, but I'm pretty sure there would be contamination from the metal of the container.

[efalconi]

It's okay to do that but understand that there will be less of the sonicating effect. Larger sonicator usually means higher ultrasonic power, I feel that mine with 2l capacity and 80W power is just strong enough. So I suggest you don't go lower than that. You could use the sonicator's container to irradiate the mixture to a greater effect than if you have it in a beaker sitting in a water bath, but I'm pretty sure there would be contamination from the metal of the container.

Thanks for the reply karusel. I'll keep that in mind. BTW. What sonicator are you using for your set up?

[OxC]

A guy on a Facebook discussion group has been doing some interesting lab tests. He claims to have measured encapsulation efficiency and particle sizing of this "Very High Potency Liposomal Vitamin C."

[karusel]

^^^^^^Thank you for this!!

efalconi: Ulsonix Proclean 2.0DS

Presently, I am struggling to find studies to confirm any easy method for producing liposomes. My findings are that there are several different procedures, using various solvents with mixed results, some have higher and some have lower yields of encapsulation, it appears that using ethanol as a solvent and hydrophilic solution of the drug to be encapsulated does not produce high encapsulation rate. I am not very optimistic at this point.

[norma67]

[bryan2]

I'm new to all this and to this discussion but wonder if anyone can comment on this process - it doesn't mention any alcohol or solvent and appears simple to accomplish. my apologies if I'm late in the discussion and knowledge and if it's obvious I should do more research I would appreciate any references. thanks...

http://www.ccphchicago.com/articles/Mak ... amin_C.pdf

[quintessential5]

Sorry, it's a long thread; haven't read all of it, so maybe this has already been addressed. I noticed that the OP's recipe and dosing is such that, if my calculations are right, he's getting about 14.7 g of lecithin per day. Isn't that a lot? Or did I miscalculate somehow? Discussions of lecithin dosing that I've read have indicated a max dose of about 3 g. Could it be that 3 g is maybe the point of maximum benefit but more than that isn't a bad thing? Choline provides a caffeine-like kick for me, so I know I couldn't start with something like 14.7 g of lecithin right off the bat, but maybe I could work up to it. Just not sure about safety.

Thanks!