New Method for Very High Potency Liposomal Vitamin C

Discussion of the benefits and disadvantages of commercial and homemade (DIY) liposomal vitamin C

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testingc
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by testingc » Wed Sep 28, 2016 12:41 pm

You can cool it but don't cool it below room temperature because I'm almost sure low temperature destroy liposomes.


Are you saying it needs to be consumed whilst still warm? Don't put in the fridge at all? What's the basis for this?

norma67
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by norma67 » Wed Sep 28, 2016 6:56 pm


jara_j
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jara_j » Thu Sep 29, 2016 12:28 am

testingc wrote:
You can cool it but don't cool it below room temperature because I'm almost sure low temperature destroy liposomes.


Are you saying it needs to be consumed whilst still warm? Don't put in the fridge at all? What's the basis for this?


I store it at room temperature. Alcohol conserves it and I think it's because AA solution is so concentrated that in lower temperature AA precipitates and the structure changes. May be lecithin I use has this behaviour. Definitely my product stored in refrigerator is not clear and is more sour to taste. I'm not saying that all liposomal solutions cannot be refrigerated but this one yes.

jara_j
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jara_j » Thu Sep 29, 2016 1:17 am

Last edited by jara_j on Thu Sep 29, 2016 5:14 am, edited 1 time in total.

testingc
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by testingc » Thu Sep 29, 2016 2:00 am

I think it's really dangerous for your ears to sonorize and mix the solution. Thats why I prefere this method.


Maybe wear some ear defenders? Or just walk out of the room?

I think we need to be VERY careful to quantify what is established as scientific fact, and what is just a personal preference. There's a lot of posts here about 'preferred methods', some of them contradictory or even the exact opposite recommendation to the original method that started this thread. I'm not saying they're not valid - but I'd like to see statements backed by studies or lab results that confirm them.

Has anyone sent their mixture to a lab to confirm the lipsomes? Care to share the results?

I'd be open to kicking in a few $$ for a group analysis. I'm based in the UK - if there's anyone local that wants to reach out to a lab, I'd be happy to contribute.

Kasia
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Kasia » Thu Sep 29, 2016 4:45 am

hello,
I want to ask about alcohol in the mixture- does it stay in the final product? Do kids can use it?

norma67
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by norma67 » Thu Sep 29, 2016 2:45 pm


testingc
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by testingc » Thu Sep 29, 2016 2:53 pm

Kasia wrote:hello,
I want to ask about alcohol in the mixture- does it stay in the final product? Do kids can use it?


Alcohol evaporates at 78.33C. Unless there are other chemical processes at work I'm not aware of, I imagine that means it will still be present in the final solution. Perhaps someone here can clarify?

Assuming the above is correct - Following Chris' original formula, if you used vodka, 35.6% of the final solution would be made up of it. A 60ml shot he takes every day would contain 21.36ml of vodka, equivalent to almost half a shot you'd order at a bar!

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by norma67 » Thu Sep 29, 2016 3:20 pm


jara_j
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jara_j » Fri Sep 30, 2016 12:50 am


gtrkiwi
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by gtrkiwi » Wed Oct 05, 2016 12:42 am

Hi all. I have been playing around with the various methods of producing lipo C for some time now and despite my best efforts never seem to be able to produce a brew that doesn't react to the baking soda test. I gather the bicarbonate of soda reacts with the ascorbic acid if it is free, as in not encapsulated and therefor not liposomal. I have just tried the heat method and find that in fact the bicarbonate of soda does not react when you drip it on the mix, but if you give it a bit of a stir up it starts fizzing away all the way through. Any thoughts on this as i am starting to think liposomes don't exist or will any mix fizz up when stirred? Does the fact that it doesn't fizz when dripped on mean there are liposomes formed?
With my last mix I cold mixed all the ingredients and heated in the microwave stopping every 30 seconds to check the temp. Did this all the way to 50 deg Celsius at which time I stirred while allowing to cool. I rightly or wrongly thought the microwave may have the same effect as ultasound albeit at a very different frequency. Any thoughts on this.
I am using NOW Sunflower lecithin which I am told is very high quality.
Cheers.

testingc
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by testingc » Wed Oct 05, 2016 3:47 am

gtrkiwi wrote:Hi all. I have been playing around with the various methods of producing lipo C for some time now and despite my best efforts never seem to be able to produce a brew that doesn't react to the baking soda test.


Could you explain your 'various methods' a little more in-depth, please? What exactly have you tried? Did you use Chris' original formula at http://qualityliposomalc.com/? - what strength alcohol? Blender-only or blender and ultrasonic, etc?

It'd be helpful to know exactly what you've tried, so we can rule out potential issues.

gtrkiwi wrote:With my last mix I cold mixed all the ingredients and heated in the microwave stopping every 30 seconds to check the temp. Did this all the way to 50 deg Celsius at which time I stirred while allowing to cool. I rightly or wrongly thought the microwave may have the same effect as ultasound albeit at a very different frequency. Any thoughts on this.


Where did you get the idea that microwaves are a replacement for ultrasonic? I'm genuinely curious - I've never seen any recommendations that say one can be replaced with the other. Chris' formula calls for sticking to a certain temperature range. How do you control that? He recommends using the ultrasonic in batches until 32C is reached, for a total of ~1 hour of irradiation. What's the assumed equivalent in using a microwave?

gtrkiwi wrote:I am using NOW Sunflower lecithin which I am told is very high quality.


Have you tried with soy lecithin in Chris' formula? Many of the issues with viscosity people seem to be having here, seems to be a result of choosing a different kind of lecithin. For your first batch, I'd stick as closely as possible to the brands and formula he uses, or you're just introducing new variables that haven't been tested.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by jara_j » Thu Oct 06, 2016 1:39 am

gtrkiwi wrote:I have just tried the heat method and find that in fact the bicarbonate of soda does not react when you drip it on the mix, but if you give it a bit of a stir up it starts fizzing away all the way through.

That supports my experience, if you want to get clear fluid, don't stir it while cooling and let it few hours in quiet. You get almost transparent fluid and then if you stir it, it changes to milky. Particles becomes bigger and some of them may destroys.

gtrkiwi wrote:I rightly or wrongly thought the microwave may have the same effect as ultasound albeit at a very different frequency. Any thoughts on this.

I don't think so, it's only temperature efect, you can use infrared lamp or other heat source to make this. I tried it. I use microwave because it is fast so minimum of C is lost.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post by gtrkiwi » Wed Oct 12, 2016 2:55 am

Back again, various methods......
started with the you tube type method, simply soak, blend, and then ultra sound directly in the machine whilst stirring. Would not have a clue whether liposomes were formed or not, VC does not seem to have too much effect on number twos for me or maybe this method really worked? Didnt know about testing with baking soda at this stage.
Then I found Chris's website, www.qualityliposomalc.com and began making my brews according to the instruction given there. Seemed to be well researched and written so I had been using this method keeping the temperature below 32 deg Celsius and following the steps as laid out.
Alcohol content from memory is about 12%. Used sunflower lecithin as there are a lot of negatives surrounding soy, even non GM stuff so avoided it.
Also used borosilicate glass beakers to ultra sound in. I was as scientific and precise as I could be making the stuff but it always seemed to react to baking soda test.
Then I found the "new" heating method. If liposomes are formed at transition temp of around 45 C as the lecithin cooled, I wondered then if Chris was correct is stating lipsomes were destroyed or began to deteriorate at temperatures over 32 C.
So I began making brews using the heat method to produce HM liposomes. I first heated on the stove in a pot stirring the whole time and checking the temp using an infra red thermometer. Then added the VC as it cooled and ultra-sounded when finished. Used glycerin and alcohol. I wondered if the alcohol remained after coming into contact with heat. I suspect it evaporated out pretty quickly.
My last brew I pre mixed all the ingredients and then began heating in the microwave. Used 20 second bursts and then stirred and checked the temp with my infra red thermometer. Took it up to about 47 C and stirred until cooled down. I did not ultra-sound this brew. This is the mix that did not react to the baking soda, that is until i stirred it. then it fizzed all the way through.
The Idea of the microwave is not based on any thing in particular. I simply thought that because microwaves heat using radio waves that agitate and vibrate water molecules at an atomic level, then maybe the micro waves could help form liposomes just as ultra-sound does. As I said, no clue whether or not science supports my brain wave. Probably best still ultra-sound.
Cheers.

Jacquie
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Re: New Method for Very High Potency Liposomal Vitamin C

Post by Jacquie » Wed Oct 12, 2016 2:30 pm

No additional information to add to the making of liposomal C, but I did want to say I really appreciate the way the posters in this thread are trying to be as specific and careful as possible in describing their methods and results in attempting to make lipo. It makes the quality of the information here pretty outstanding and useful, and helps in my attempts (and others I've talked to who've read it) to improve on my own lipo making. Thank you to all.


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