That is a Great proposal, ChristopheG.
Might you want add a base line in there too, using a standardized lipo like LivOn or the like?
all for now...
norma67 wrote:I have tried to attach some photos, but I didn't succeed, or I haven't understood the procedure explained here in the forum.
How is it done?
Cdizzle wrote:thanks for the write-up!
So I'm assuming you store the mixture at room temperature? Does it spoil after a week or two?
Johnwen wrote:OMG !!! Is all I can say from what I’m reading in these posts.
Drinking per se Liposome / Vodka cocktails first thing in the morning I don’t think and know that this isn’t going to give any benefits!
So I thought, what’s the fastest and most efficient method I could convey to this group of DIY’ers.
Right now there’s about 25 different methods of encapsulation that are in use and I opted to show the simplest which can yield up to 90% encapsulation. However it only yields SUV’s but for this purpose should suffice. It’ll also give sobering results!!
If you have studied lipids you know that the head turn to liquid and the tail stays away from it. So the head is hydrophilic and the tail is hydrophobic.
However it has been found that this also applies to certain solvents also and when this reaction occurs theses lipid’s also cluster together to form a liposome or a sphere of individual lipids. Ethanol is a solvent that this occurs in so it is readily available in most states as pure grain alcohol or 180 proof white lighting. In commercial production various other forms of this product are used but require refined purification methods are needed to remove the byproducts.
In the following I’m going to outline how this process works!
I’m leaving out the details of quantity because there are so many variables that only experimentation of amounts would be a individual preference!
In the first step were going to institute this reaction.
We take a beaker and add the ethanol to it, then take a slightly smaller amount of lipids and blend the two together gently. This forms the liposome’s. Wait at least 10 minutes to allow for this reaction!
DO THIS OUTSIDE ANY STRUCTURE IN OPEN AIR!!
Next is evaporation Ethanol has a flash point of 61.9* F so it don’t take much heat to get it to disappear without damage to the liposome’s. As you can imagine the flash of water is @ 212*F and at that temp. your cooking the liposome’s. I would say that water at 100*F in the tray should give rapid results in evaporation. Once again remember your working with a flammable liquid here and it’s vaporized making it more flammable. Once the ethanol has disappeared and the liposome’s are dry. Remove the beaker and let it cool to ambient temperature.
Now mix your Ascorbic acid and water you want a mix that is just above a paste. So Put you AA in first then add water and stir till it’s a moveable liquid. Keep a little bit of the AA mix here!
Now add this to the Dry Lipo’s. and gently agitate to get it to blend together. Don’t shake or stir just a gentle movement.
Now get out the ultrasound this method depends on the power of your unit! If it’s High power you can keep it in the beaker and zap it in surrounding water.
Low power, pour mix into unit and add the left over AA mix as a rinse for the beaker.
Zap it till mix looks blended if not keep zapping till it looks mixed.
You now have Lipo-C but to get out the residuals for the highest encapsulation it should be filtered. The best way is a gentle centrifuge. However your talking $$!! Or you could just set it a side for awhile and let the good stuff settle to the bottom and pour off the residual which is AA and water and blank liposome’s! So it’s drinkable!! The muddy stuff on the bottom is what it’s all about! That’s your Liposome AA!!
Hope this helps with your health and sobriety!!!
karusel wrote:It's okay to do that but understand that there will be less of the sonicating effect. Larger sonicator usually means higher ultrasonic power, I feel that mine with 2l capacity and 80W power is just strong enough. So I suggest you don't go lower than that. You could use the sonicator's container to irradiate the mixture to a greater effect than if you have it in a beaker sitting in a water bath, but I'm pretty sure there would be contamination from the metal of the container.
OxC wrote:A guy on a Facebook discussion group has been doing some interesting lab tests. He claims to have measured encapsulation efficiency and particle sizing of this "Very High Potency Liposomal Vitamin C."
I made an acceptable batch. I do not have any litmus left, but it tastes near to neutral.
I nixed the blender. N2 is still on hand as needed.
I tried Norma's recipe several times and I would see it trying to gel but always went flat and SOUR!!
I modified Norma's recipe:
30 g Now soya L
40 g Rum 40%
70 g Water
soaked 4 hr
raised to 49*C for ~ 10 min
20 g Vit C (cassava based, I am an O! I never realized how bad corn based (LivOn) made me feel until now. I know that type A people do tolerate corn)
50 g water
Kept at 36*C but only ~ 2 min prior to,
pulling step 1 @45*C and dribbling step 2 into 1, stiring & etc, in a very chilly kitchen.
It gelled up nicely. I stored in fridg (HVACR guys have cold (35* F) fridg's). Then went shopping for the sonicator. I found a Harbor Freight 35 W baby. It needed lots of modding to work right.
The short 3 min duty cycle needed fixing: wimpy heat sinks, trashing the body, shorting the relay so the power plug is my power switch, among other things...(PM me for NON UL Mods). It works now for hours straight.
It went in the sonicator pan, naked, like some fab pudding all shiny.
So after blasting it for 45 min (in my fridg) the pudding went flat! It never went over 25*C, incl stiring.
It still had some body and the Ph did not change.
For dosing I just add all masses and divide by 20. I have a $20 250g 10mg resolution scale I bought at a Pot shop.
If I never cool the batch the PH rises and thickens in 24 hrs.
If I keep it at 35* F it drops and thins out.
Thanks to Everybody and especially Norma
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