Dehydroascorbic acid in liposomal solution?

Discussion of the benefits and disadvantages of commercial and homemade (DIY) liposomal vitamin C

Moderator: ofonorow

RatherBeUnknown
Enthusiast
Enthusiast
Posts: 123
Joined: Wed Jun 01, 2016 5:30 am
Contact:

Dehydroascorbic acid in liposomal solution?

Post Number:#1  Post by RatherBeUnknown » Tue Jul 26, 2016 4:07 pm

Would this work, in making liposomal vitamin C? It's for the purpose of increasing brain and mitochondria vitc levels since DHAA is able to cross the BBB and mitochondria where AA is not.

tjohnson_nb
Vitamin C Expert
Vitamin C Expert
Posts: 548
Joined: Thu Apr 26, 2012 5:03 am
Location: Canada
Contact:

Re: Dehydroascorbic acid in liposomal solution?

Post Number:#2  Post by tjohnson_nb » Wed Jul 27, 2016 11:18 am

Reduced ascorbate enters the CNS by a different route.
The major route by which ascorbate enters the CNS involves transport from plasma to the CSF across the epithelium of the choroid plexus

See http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649700/figure/F2/
'Always' and 'never' are 2 words you should always remember never to use.

RatherBeUnknown
Enthusiast
Enthusiast
Posts: 123
Joined: Wed Jun 01, 2016 5:30 am
Contact:

Re: Dehydroascorbic acid in liposomal solution?

Post Number:#3  Post by RatherBeUnknown » Wed Jul 27, 2016 12:34 pm

tjohnson_nb wrote:Reduced ascorbate enters the CNS by a different route.
The major route by which ascorbate enters the CNS involves transport from plasma to the CSF across the epithelium of the choroid plexus

See http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649700/figure/F2/

By reduced you mean DHAA? Could you explain further since I don't understand the implications. Does the drawing suggest that ascorbic acid can enter the bbb just as DHAA can?

tjohnson_nb
Vitamin C Expert
Vitamin C Expert
Posts: 548
Joined: Thu Apr 26, 2012 5:03 am
Location: Canada
Contact:

Re: Dehydroascorbic acid in liposomal solution?

Post Number:#4  Post by tjohnson_nb » Thu Jul 28, 2016 8:08 am

No, DHAA is oxidised AA. The article suggests that there is another way for AA to enter the CNS besides the BBB, in fact, it is the main way for AA to enter - across the epithelium of the choroid plexus.
'Always' and 'never' are 2 words you should always remember never to use.


Return to “Liposomal Vitamin C”

Who is online

Users browsing this forum: No registered users and 2 guests