Scientists have extended the lifespan of mice by up to 35 percent - with no adverse effects

Catch-all for other anti-aging techniques, e.g. Audrey De'Gray

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Scientists have extended the lifespan of mice by up to 35 percent - with no adverse effects

Post Number:#1  Post by ofonorow » Fri Feb 05, 2016 4:53 am

http://www.sciencealert.com/scientists-have-extended-the-lifespan-of-mice-by-up-to-35-percent-with-no-adverse-effects

A new study has shown that the lifespans of mice can be extended by up to 35 percent by simply clearing out senescent cells - defunct cells that stop dividing, accumulate in old age, and trigger inflammation in fat, muscle, and kidney tissues.

Not only did the mice experience significantly longer lifespans thanks to removal of these cells, but the treatment also delayed the onset of age-related disorders such as heart and kidney deterioration, and the development of cataracts and tumours


This made the news because it may form the basis of a new drug. From the first reading, this sounds like what happens from modulating or correcting the normal apoptosis, where the body kills and cleans out these cells on its own. And the finding near the end of life, reminds one of the elegant Harvard study that grew telomeres in mice. They didn't notice much during middle age. Things got interesting only when the mice telomeres becamse extremely short near the end of life. In other words, short telomeres may interfere with the normal apoptosis mechanism.
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