Yet patients are not being warned that the drug also lowers levels of vitamin B12 and this can trigger peripheral neuropathy - a form of nerve damage which affects around half of all people suffering from diabetes.
Peripheral neuropathy weakens cardiac tissue, increasing the risk of a heart attack, and causes ulcers which refuse to heal and result in an average of 20 amputations a day.
This nerve damage is most commonly caused by prolonged high blood sugar levels.
However it can also be caused by a deficiency of vitamin B12, and dozens of studies confirm that metformin disrupts our ability to absorb this nutrient.
I don't know if the above is true, but I do know that Life Extension has long touted METFORMIN, especially because of the reduction of risk of pancreatic cancer in those who take it. If the above is true, then making sure vitamin B12 levels are adequate would be important.