Antioxidants helps retinopathy in diabetes caused by insulin

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Antioxidants helps retinopathy in diabetes caused by insulin

Post Number:#1  Post by ofonorow » Mon Jul 16, 2012 1:57 am

Another reason for diabetics to take more vitamin C.

http://www.ncbi.nlm.nih.gov/pubmed/22695936
Supplementation with antioxidants attenuates transient worsening of retinopathy in diabetes caused by acute intensive insulin therapy.

Ascorbic acid, α-lipoic acid, and α-tocopherol also decreased superoxide anion production

Insulin can increase ROS production through an NAD(P)H, phosphatidylinositol 3´-kinase-dependent mechanism in bovine retinal microvascular endothelial cells ex vivo. ROS can regulate insulin-induced VEGF expression. Supplementation with antioxidants may help to attenuate the transient worsening of retinopathy in diabetes caused by acute intensive insulin therapy.
Owen R. Fonorow, Follow #OWENRFONOROW at twitter

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