Its a general principle. It probably works with number of disorders.
This is an interesting theory/principle...triage-theory...
http://www.smart-publications.com/articles/dr-bruce-ames-proves-his-triage-theory-of-micronutrients-with-vitaminthat the body takes what it needs from where-ever possible, and prioritizes according to an internal biological unconscious scale of necessity, 24/7...and any core-vulnerability that is eventually exposed by this prioritizing, might leave the DNA more open than usual for mutations...however...this way of thinking might be appropriate for understanding already manifest and recognized genetic diseases, such as in the paper referred to above...where the genetic "damage" or at least "change" has already happened, and the individual has a manifest and diagnosed genetic "disease" or "disorder"...which can perhaps, according to Ames, be alleviated by appropriate megadoses of vitamins and/or minerals, thus making the best of what can be done...but when an individual is not yet diagnosed with a genetic disease, I imagine that there would be a whole lot of "epigenetic factors" that would have to change first...perhaps this is part of the picture in all the "ordinary" diseases, which have not yet progressed into a "full-blown" genetic one? ... as for example Ehlers-Danlos syndrome, of which there are at least six! different types? It says here what specific genes are involved...
http://ghr.nlm.nih.gov/condition/ehlers-danlos-syndromebut on the other hand, it says on this page that also epigenetic factors are involved when it comes to collagen-disruption in cancer...
The available, albeit limited, information suggests that the multiple epigenetic mechanisms are engaged in the selective regulation of the transcriptional activity of MMPs, TIMPs and their ECM collagen substrates in cancer compared with normal tissue.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138141/So, until one is actually diagnosed with a genetic mutation in some gene, one might perhaps be able to change and enhance the epigenetics with supplementation before any real damage is done to the actual gene...?