Testimony - Its the Dosage Stupid!

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Testimony - Its the Dosage Stupid!

Post Number:#1  Post by ofonorow » Thu Sep 24, 2009 3:40 am

Hi Owen
9/22/09
First, Thank you for activating my account for the forum. I hope I can be of some help here.
My wife who had triple bypass in 2001 and then had an aterery closing down when I started her on Tower heart technolgy, and then they were going to do a brachetherapy (radiation burning of the artery) and found out she didn't need it.

Thanks to heart tech! She is doing just fine. She takes 3 grams C and 2.5 grams L-lysine ,1-250 mg L-Proline, 1-30 mg. CQ10. Two months ago they had to take her off one of her BP med's. She was taking 1 am & 1 pm Her Bp dropped now she only takes the am BP med now. She takes a hormone pill and That @#$$%^ Plavix. That's it. Me and her cardiologist (the same guy who wanted to burn her) had it out again about plavix the last time we were there. She still laughs when we talk about it she says she didn't understand a word of what we were talking about. Anyway she now only takes 1/2 of a pill. Per
Dr's Order! 1/2 to much for my liking.

I'd like to relay an experience and knowledge I encountered with my health over the last year. During my routine exam about a year ago my Dr. noticed a burp in my left carotid artery and sent me for an Echo. It turns out I HAD a 30% blockage there. I was shocked since me and the wife take the same supplements. She cleared out, I'm blocking up.

So back to the books, the Internet, the library. When I finally figured it out I really felt stupid. The whole answer broke down to one equation "Mg/Kg"

In Dr Klenner's writings he describes his dosage for the various diseases he treated with V-C and how he applied it for the individual patients using their weight and this formula.

My wife weights a 110 lbs. 49.6 Kg and I weight 195 lbs. 88 Kg. We take 3000 mg. a day. She figures at 3000/49.6=60.5 Mg/Kg V-C. Me 3000/88=34 Mg/Kg V-C I'm getting a little more then half of what she's getting. She's doing great, I'm going down hill. It was all to obvious I wasn't getting enough V-C. So up I went to 6000 mg with no problem at about 8000 mg start having a little problem but muscled thru it. Held at 8000 for three months then back down to 6000 mg. more for convince of taking it at food time. Since I use powdered V-C and L-Lysine Mixed. My L-Lysine was increased proportionately.

At the four month Echo Follow up I had a so called "Fatty Streak" in the artery. Four months later June 09 Echo. Results were "Normal, See you Next year!"
So Score another one for Vitamin C.

I'll tell you one thing about the process of healing my carotid artery it sure lets you know something is happening there. A few times it felt like someone kicked me in the neck ,now it's back to normal.

So What I learned is 34 Mg/Kg doesn't really give a whole lot of protection 50 Mg/Kg would probably be better for preventive. At 60 Mg/Kg healing starts at 90 Mg/Kg Things really start to happen. In Dr. Klenner's writings he seemed to start his dosages at 100 Mg/Kg of course he was IVing and shooting IM But he also used oral doses as follow ups at pretty good rates.

In the forum I noticed a few instances were people say things were going good at first when they took one of your products and then turned south. You rightfully tell them to titrate up but I can't help but to think how much has their weight changed. Playing with this formula I found even a five pound weight gain can put you in a different dosage range and if they were on the boarder to begin with now their heading in the wrong direction.

So there you have it Einstein Gave us E=Mc 2 and the world was amazed but did save a life? Klenner gave us Mg/Kg and no one noticed yet it could save millions of lives.

Before I let you go I came across this article That compare's Lipid Theory with the Unified Theory. Very well written in plain language.

John Wenskus

LINK Below
http://www.ourhealthcoop.com/pauling.htm


Thanks John. (If you want me to remove your name - email me).

Yes, Dosage dosage dosage. Since you are now an expert in the equation, perhaps you can contribute a table of body weight in pounds, and the appropriate dosage range in mg or grams?

Now as far as Plavix, maybe a strategy for Plavix is to contact one of the law firms involved
in the class action suits!
Owen R. Fonorow
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Re: Testimony - Its the Dosage Stupid!

Post Number:#2  Post by Johnwen » Thu Sep 24, 2009 8:25 am

Owen:
I going to E-Mail the Charts to you I can’t get them to load on the forum.
For those who want to be adventurous with a calculator Here an example.

Person weights 182 lbs. Find Kilograms: 182/2.215=82.167
Round up 83 Kg
Current user taking 3000mg. V-C. How much is my body getting?
3000/83=36.15 Mg/Kg Not a very good amount. I started developing plaque at 34 Mg/Kg after 8 years. It did keep cholesterol 190-202 which means I’m still alive.
50 Mg/Kg is a better amount for preventive. How to get there.
50x83=4150mg V-C. 1 Teaspoon Tower Heart Tech = 1500 Mg. V-C
4150/1500= 2.76 Teaspoons. That’s pretty hard to measure let’s round up.
3 Teaspoons . Sounds Like Breakfast, Lunch and Dinner to me. But it’s a pretty long time between Diner and Breakfast. So lets do Breakfast, Dinner and about an hour before bed. Much Better.
How much do I get now? 3 x 1500 =4500Mg. V-C
4500 / 83 =54.21 Mg/Kg That’s a good preventive amount.
My wife healed a severe blockage that formed after 3 bypass. The thing here is her blockage was fresh and formed within one week after her surgery.
61Mg/Kg healed her in one month. In me it took 4 months at 90 Mg/Kg to break up a 30% in my cartoid. As we can see Time the blockage has been there and percentage of blockage play a big role.
What’s Next?
Call Tower and reset your auto-ship. THEN:60 Teaspoons per jar. 2 a day =30 days. NOW: 60 Teaspoons per jar. 3 a day = 20 days.
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Re: Testimony - Its the Dosage Stupid!

Post Number:#3  Post by Johnwen » Thu Sep 24, 2009 8:26 am

Code: Select all

Weight Lbs. Wgt Kg. 30 Mg/Kg 40 Mg/Kg 50 Mg/Kg 60 Mg/Kg 70 Mg/Kgs 80 Mg/Kg 90 Mg/Kg 100 Mg/Kg
    100      45.1   1,354    1,806    2,257    2,709    3,160     3,612    4,063    4,515
    105      47.4   1,422    1,896    2,370    2,844    3,318     3,792    4,266    4,740
    110      49.7   1,490    1,986    2,483    2,980    3,476     3,973    4,470    4,966
    115      51.9   1,558    2,077    2,596    3,115    3,634     4,153    4,673    5,192
    120      54.2   1,625    2,167    2,709    3,251    3,792     4,334    4,876    5,418
    125      56.4   1,693    2,257    2,822    3,386    3,950     4,515    5,079    5,643
    130      58.7   1,761    2,348    2,935    3,521    4,108     4,695    5,282    5,869
    135      60.9   1,828    2,438    3,047    3,657    4,266     4,876    5,485    6,095
    140      63.2   1,896    2,528    3,160    3,792    4,424     5,056    5,688    6,321
    145      65.5   1,964    2,619    3,273    3,928    4,582     5,237    5,892    6,546
    150      67.7   2,032    2,709    3,386    4,063    4,740     5,418    6,095    6,772
    155      70.0   2,099    2,799    3,499    4,199    4,898     5,598    6,298    6,998
    160      72.2   2,167    2,889    3,612    4,334    5,056     5,779    6,501    7,223
    165      74.5   2,235    2,980    3,725    4,470    5,214     5,959    6,704    7,449
    170      76.7   2,302    3,070    3,837    4,605    5,372     6,140    6,907    7,675
    175      79.0   2,370    3,160    3,950    4,740    5,530     6,321    7,111    7,901
    180      81.3   2,438    3,251    4,063    4,876    5,688     6,501    7,314    8,126
    185      83.5   2,506    3,341    4,176    5,011    5,847     6,682    7,517    8,352
    190      85.8   2,573    3,431    4,289    5,147    6,005     6,862    7,720    8,578
    195      88.0   2,641    3,521    4,402    5,282    6,163     7,043    7,923    8,804
    200      90.3   2,709    3,612    4,515    5,418    6,321     7,223    8,126    9,029
    205      92.6   2,777    3,702    4,628    5,553    6,479     7,404    8,330    9,255
    210      94.8   2,844    3,792    4,740    5,688    6,637     7,585    8,533    9,481
    215      97.1   2,912    3,883    4,853    5,824    6,795     7,765    8,736    9,707
    220      99.3   2,980    3,973    4,966    5,959    6,953     7,946    8,939    9,932
    225     101.6   3,047    4,063    5,079    6,095    7,111     8,126    9,142   10,158
    230     103.8   3,115    4,153    5,192    6,230    7,269     8,307    9,345   10,384
    235     106.1   3,183    4,244    5,305    6,366    7,427     8,488    9,549   10,609
    240     108.4   3,251    4,334    5,418    6,501    7,585     8,668    9,752   10,835
    245     110.6   3,318    4,424    5,530    6,637    7,743     8,849    9,955   11,061
    250     112.9   3,386    4,515    5,643    6,772    7,901     9,029   10,158   11,287
    255     115.1   3,454    4,605    5,756    6,907    8,059     9,210   10,361   11,512
    260     117.4   3,521    4,695    5,869    7,043    8,217     9,391   10,564   11,738
    265     119.6   3,589    4,786    5,982    7,178    8,375     9,571   10,767   11,964
    270     121.9   3,657    4,876    6,095    7,314    8,533     9,752   10,971   12,190
    275     124.2   3,725    4,966    6,208    7,449    8,691     9,932   11,174   12,415
    280     126.4   3,792    5,056    6,321    7,585    8,849    10,113   11,377   12,641
    285     128.7   3,860    5,147    6,433    7,720    9,007    10,293   11,580   12,867
    290     130.9   3,928    5,237    6,546    7,856    9,165    10,474   11,783   13,093
    295     133.2   3,995    5,327    6,659    7,991    9,323    10,655   11,986   13,318
    300     135.4   4,063    5,418    6,772    8,126    9,481    10,835   12,190   13,544
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Re: Testimony - Its the Dosage Stupid!

Post Number:#4  Post by ofonorow » Sat Sep 26, 2009 5:27 am

Cool, thank you. This is the Fred Klenner range, however based on your recent experience, which column do you believe represents the minimum therapeutic dosage based entirely on body weight (and no other factors). Maybe we should bold that column?

This is an interesting way of thinking about vitamin C supplementation, especially for health professionals. But somewhat complex. Perhaps we may still be able to reduce the seemingly complicated table by looking at it another way, e.g.

2000 mg Weight A thru B
2500 mg Weight B thru C
3000 mg Weight C thru D, etc.

Owen R. Fonorow
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Re: Testimony - Its the Dosage Stupid!

Post Number:#5  Post by Johnwen » Sat Sep 26, 2009 8:20 am

I Posted the chart more for speed to get it up. People can see what their intake is in comparison with their weight. I’ve been researching what the experts say as far as what the minimum amount we should be taking is.
Thru my observations and personal experiences my feeling’s are that 50 Mg/Kg a day. Should be a base amount taken to maintain good health an give the body a defense. The following are from the Experts.
Fredrick Klenner: Quote
“Based on scant data on mammalian synthesis, available for the rat, a
70-Kg. individual would produce 1.8 grams[5] to 4.0 grams[6] of ascorbate per day in the unstressed condition. Under stress, up to 15.2 grams.”
Ok! Unstressed means “Not Sick”
70-Kg.=155 Lbs. Math: 1800Mg/70= 25.71 Mg/Kg to 4000Mg/70= 57.15 Mg/Kg. Let’s Average it out 25.71+57.15=82.86/2=41.43 Mg/Kg would be the average amount available in a healthy155lb. Person. If We were able to synthesize Vitamin C Like a Lab Rat does.
Irwin Stone: Quote
“From the Committee on Animal Nutrition's "Nutrient Requirements of Laboratory Animals" (1962) we find some startling figures. The recommended diet for the monkey -- our closest mammalian relative -- is 55 milligrams of ascorbic acid per kilogram of body weight or 3,830 milligrams of ascorbic acid per day for the average adult human. The daily amount suggested as adequate for the guinea pig varies depending upon which of two diets is selected and ranges from 42 to 167 milligrams per kilogram of body weight (based on a 300-gram guinea pig). This amounts to 2,920 milligrams to 11,650 milligrams per day for the average adult human.”
Average adult= 155lbs.-70 Kg
I Like Dr. Stone he did all the math for me. I’m Doing more checking on this so we can find a good base. Let’s average this out 41.43+55=96.43/2=48.215Mg/Kg.
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Re: Testimony - Its the Dosage Stupid!

Post Number:#6  Post by ofonorow » Tue Sep 29, 2009 3:56 am

Thank you for the work. Is the Klenner range for oral intake? (Pauling estimated that 50% is lost via oral route)
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Re: Testimony - Its the Dosage Stupid!

Post Number:#7  Post by Johnwen » Sat Oct 03, 2009 4:16 pm

Sorry I took so long responding had to prepare a paper for my daughter. She's an RN
Here's a link that pretty much says the more you Take with each Dose the less you absorb. Ie More smaller doses are better then a few large doses. Good Reading

http://www.exrx.net/Nutrition/Antioxida ... aminC.html
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Re: Testimony - Its the Dosage Stupid!

Post Number:#8  Post by scottbushey » Sun Oct 04, 2009 4:37 am

"More smaller doses are better then a few large doses."

Greetings. New to the board, new to Vitamin C therapy.

Having read this interesting thread, would the following be efficacious to my intake?
This am, I took 4 grams powder VC and put it in a new .5 liter bottle of H2O; my goal is to drink this over a 4 hr span. take an additional 2 grams in pill form at noon, then another 4 Gram solution.

Kind regards,

Scott

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Re: Testimony - Its the Dosage Stupid!

Post Number:#9  Post by ofonorow » Sun Oct 04, 2009 5:02 am

Welcome. 6000 mg daily for a healthy person is a good amount. This amount (due to loss of 50% in 4 hours in water) is in theory between 4 and 5 grams daily. Have you calculated your "unsick" bowel tolerance ( http://www.orthomed.com/titrate.htm)? As we recently posted, 80% of the may require 10 g daily for best of health. The bowel tolerance "test" will help you determine your daily requirement.
Owen R. Fonorow
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Re: Testimony - Its the Dosage Stupid!

Post Number:#10  Post by scottbushey » Sun Oct 04, 2009 5:05 am

I don't quite understand how to calculate that. Can you help?

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Re: Testimony - Its the Dosage Stupid!

Post Number:#11  Post by Johnwen » Mon Oct 05, 2009 4:08 pm

Scott I’m going to assume your in good health and someone or something made you aware that you maybe in line for problems down the road. What your doing by watering down the powder and leaving it set, cuts it’s potency in half so if you put 4 grams in it your only getting the effect of 2 grams also your exposing your teeth to an acid. Just like happens when you sip soda all day. The better way would be to mix small amounts with water then drink it and chase it with some water. That way your getting with your paying for. If that don’t work for you, have a bottle of regular water for a rinse after your drink. Your method with the pill would yield 6000 mg V-C Effective. Look up at the chart on the left side find your weight and then follow to the right and find 6000 or around it and look at the top that is your milligrams of V-C per kilogram of body weight. 50 would give you pretty good protection. Owen wants you to titrate up to find your bowel tolerance. I would suggest holding at your 6000mg for about two weeks so your body can get use to the new nourishment it’s receiving. About every 3 days add another 500mg V-C to your routine. Make sure you write down what your taking per day at some point down the road your gut is going to let you know. That is bowel tolerence. What you just found out is your unstressed limit. Back it down 500 mg and that is what body needs. If after a couple of days your gut acts up. It means you weren’t a 100% well and now your better and your body don’t need the higher amount any more. Everybody is different Everyday is different. Soon you’ll have a good target amount of V-C Don’t forget L-Lysine Min.2800 Mg. Min. L-Proline 250Mg. And a Multi Vitamin. Hopefully your healthy enough were you don’t have to go too much over 6000.
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Re: Testimony - Its the Dosage Stupid!

Post Number:#12  Post by Johnwen » Mon Oct 05, 2009 4:56 pm

Owen and people of the forum I had an epiphany today and like to get some feed back on this idea. On the chart at the top it gives the Mg/Kg amounts. What if That was the decade of age? Of a healthy individual.
Lets say a 42 year old person weighting 185 lbs. We look at the 40 Mg/Kg column and go down to 185 lbs on the left it intersects at 3341 mg V-C or 3500mg would be a good healthy, protective base. A 48-49 year old would be best to go to the 50 column. The vitamin C experts kind of avoid giving a good base amount. Dr. Pauling said 3000 mg would prevent 75% of the problems and he verified this in his tape but I believe he was like the others going against the ridicules 60mg RDA. Looking at the chart 3000 mg would protect quite a few weight ranges some more then others yes 75% of the population would be protected but what about the 1 in 4 that it don’t protect?
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Re: Testimony - Its the Dosage Stupid!

Post Number:#13  Post by ofonorow » Wed Oct 07, 2009 3:19 am

I feel a little thick today and I am not following. Are you saying that you think the aged require more antioxidant protection? Probably true, but how would we quantify? What experiment could be run?

The beauty of your original epiphany is the recognition that body weight (to the extent it represents the number of cells) is important when deciding on vitamin C dosages. What is the extension, and is it worth the complication?
Owen R. Fonorow
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Re: Testimony - Its the Dosage Stupid!

Post Number:#14  Post by Johnwen » Wed Oct 07, 2009 10:30 am

Statistical Analysis is always a good indicator.
Here’s a link to the National Center for Health Statistics, Heart disease statistics. It’s 169 pages long in it you can find anything about any possibility that’s been reported to the CDC. It’s overwhelming.

http://www.cdc.gov/nchs/data/series/sr_10/sr10_240.pdf

On this one it’s less confusing they took the info and Graphed it On Page #5
Click on PDF file at bottom of text.

http://www.sourceadvisorsinc.com/report.php?id=18

With this information I can say “ Yes! Age Does Factor into Heart Problems.”
BUT living in Alabama and along the Mississippi & Ohio River also seems to Raise your risk. Evidence link here.

http://www.cdc.gov/DHDSP/library/fs_men_heart.htm
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Re: Testimony - Its the Dosage Stupid!

Post Number:#15  Post by ofonorow » Thu Oct 08, 2009 8:06 am

The question is what is the relation between age and vitamin C intake.
Owen R. Fonorow
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