NiacinVC wrote:Also I goto a doctor and get vitamin c injected into my deltoid twice a week and I notice an almost euphoric feeling shortly after being injected with vitamin c( I dont experience this from oral vitamin c).
Jacquie wrote:Whoa... if you don't mind me asking, how'd you get the doc to give you C injections?
Sustained release niacin is hepatotoxic with doses larger then 1g
Four serious cases have been reported, all involving a sustained release preparation. Mullin, Greenson & Mitchell (1989)  reported that a 44 year-old man was treated with crystalline nicotinic acid, 6 grams daily, and after 16 months was normal. He then began to take a sustained-release preparation, same dose. Within three days he developed nausea, vomiting, abdominal pain, dark urine. He had severe hepatic failure and required a liver transplant. Henkin, Johnson & Segrest found three patients who developed hepatitis with sustained release nicotinic acid. When this was replaced with crystalline nicotinic acid there was no recurrent liver damage. 
sjmusic2 wrote:You can buy your own shots and needles at http://www.b12-shot.com/ , they're in Canada but will ship to the US.
sjmusic2 wrote:Sorry Jacquie, I don't have any knowledge of methyl- or hydroxy- cobalamin sources - actually had to google it to find out the differences and benefits over cyanocobalamin !
I have bought the Vitamin C injectables from b12-shot.com though and the process was very smooth. I take cyanocobalamin orally and have found my levels rise quickly with this method - I use custom capsule (http://www.customcapsule.com) to design my own supplements.
pamojja wrote:I think with hepatoxic he meant that liver enzymes often do rise above reference ranges if sustained release niacin is taken at high doses or twice a day. My own started to go higher at about 3 gram/day immediate release niacin. By dosing every second day (7 grams now) liver enzymes normalized again.
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