New Method for Very High Potency Liposomal Vitamin C

Discussion of the benefits and disadvantages of commercial and homemade (DIY) liposomal vitamin C

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pamojja
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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#166  Post by pamojja » Tue Oct 31, 2017 5:19 pm

As far as I know up to 10 gram of Soy lecithin per day have been used:

http://healthlibrary.epnet.com/GetConte ... kiid=21680

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#167  Post by quintessential5 » Tue Oct 31, 2017 5:54 pm

As far as I know up to 10 gram of Soy lecithin per day have been used:

http://healthlibrary.epnet.com/GetContent.aspx?token=5b000b40-3809-4cb2-88a4-68bfd31b5c51&chunkiid=21680


Thanks! That's very helpful.

From that document:

European research has tended to use products concentrated to contain 90% phosphatidylcholine in lecithin, and the following dosages are based on that type of product. For psychological and neurological conditions, doses as high as 5 to 10 g taken three times daily have been used in studies. For liver disease, a typical dose is 350 to 500 mg taken three times daily; for high cholesterol, 500 to 900 mg taken three times daily has been tried.


So, it seems that even up to 30 g a day has been used in at least one study. Very cool!

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#168  Post by marush » Sun Feb 18, 2018 8:08 am

qualityliposomalc wrote:I'm glad you liked the site.

If you end up making some liposomal C using the recipe please me know how it turns out!

Thanks,

Chris


My husband and I use your recipe and it turns out great, is very effective!

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#169  Post by skwoodwiva » Tue Mar 06, 2018 7:32 pm

norma67 wrote:
OxC wrote:A guy on a Facebook discussion group has been doing some interesting lab tests. He claims to have measured encapsulation efficiency and particle sizing of this "Very High Potency Liposomal Vitamin C."


For who doesn't use FB, could some one be so kind to refer the results here? thanks


skwoodwiva wrote:Success!
I made an acceptable batch. I do not have any litmus left, but it tastes near to neutral.
I nixed the blender. N2 is still on hand as needed.
I tried Norma's recipe several times and I would see it trying to gel but always went flat and SOUR!!

I modified Norma's recipe:
30 g Now soya L
40 g Rum 40%
70 g Water
soaked 4 hr
raised to 49*C for ~ 10 min

2nd step
20 g Vit C (cassava based, I am an O! I never realized how bad corn based (LivOn) made me feel until now. I know that type A people do tolerate corn)
50 g water
Kept at 36*C but only ~ 2 min prior to,
pulling step 1 @45*C and dribbling step 2 into 1, stiring & etc, in a very chilly kitchen.
It gelled up nicely. I stored in fridg (HVACR guys have cold (35* F) fridg's). Then went shopping for the sonicator. I found a Harbor Freight 35 W baby. It needed lots of modding to work right.

The short 3 min duty cycle needed fixing: wimpy heat sinks, trashing the body, shorting the relay so the power plug is my power switch, among other things...(PM me for NON UL Mods). It works now for hours straight.
It went in the sonicator pan, naked, like some fab pudding all shiny.
So after blasting it for 45 min (in my fridg) the pudding went flat! It never went over 25*C, incl stiring.
It still had some body and the Ph did not change.

For dosing I just add all masses and divide by 20. I have a $20 250g 10mg resolution scale I bought at a Pot shop.

Edit,
If I never cool the batch the PH rises and thickens in 24 hrs.
If I keep it at 35* F it drops and thins out.

Thanks to Everybody and especially Norma


As I mentioned in some of my earlier posts, the recipe can vary due to different lecithin, alcohol grade, so I am glad you have found the solution that fits your ingredients and it is useful for you.


I had a private message asking for informations regarding the transition temperature, and since I think this could be useful to others, I will reply here in the topic.

The transition temperature is the moment of the transformation of the lecithin from the liquid state (liquid crystals) to the solid state or gel (liposomes).
The temprature can vary from the composition of the lechitin and the lipids added, so the first time I heated the lechitin compound, I tested the melting point of the one I have used.
Since the C vitamin is sensible to heating, I have indicated a temperature just above the the limit.
The lecithin compound can be heated to a higher temperature and then cooled down to about 42-45 °C, before adding the C vitamin ( in a way to protect it ) and then stirring until it forms the liposomes.

“Formation of liposomes is only possible, if the temperature of the sample is above the transition temperature. According to [2], the transition temperature of liposomes consisting of pure lipids is 41.4 °C, whereas lipids from natural origin such as lecithin containing fatty acid mixtures exhibit a broad transition range [3]. The upper limit for liposome formation is the Krafft point of lecithin, which is at a temperature of 58 °C [4]. Therefore the temperature range between 41.4 °C and 58.”
ref.: http://www.pharmtech.tu-bs.de/files/muegoy/MMuellerHalle0110.pdf

searching on google there are many other researches regarding the transition temperature of the liposomes.

Thanks Norma,

I can afford to buy Livon now...

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#170  Post by ISMA » Sun Mar 25, 2018 12:13 pm

Dear Chris,

Why do you prefer lecithin granules than liquid lecithin?

For me it is difficult to find sunflower lecithin granules.

Thank you very.

Isma.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#171  Post by infinitey » Thu Mar 29, 2018 4:00 pm

I'm in the US and the easiest source of ethyl alcohol would be from the convenience store, in the form of 70% ethyl rubbing alcohol. Unfortunately, one of the inactive ingredients is acetone, which I believe is added to make it "denatured." Is it still okay to use it to make lipo C?

I tried looking for non-denatured alcohol on eBay and found that they are rather expensive. If someone could mention a dependable source for the alcohol (I am over 21), it would be appreciated.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#172  Post by BrightSideOfLife » Fri Mar 30, 2018 1:24 am

infinitey wrote:I'm in the US and the easiest source of ethyl alcohol would be from the convenience store, in the form of 70% ethyl rubbing alcohol. Unfortunately, one of the inactive ingredients is acetone, which I believe is added to make it "denatured." Is it still okay to use it to make lipo C?

I tried looking for non-denatured alcohol on eBay and found that they are rather expensive. If someone could mention a dependable source for the alcohol (I am over 21), it would be appreciated.

Rubbing Alcohol is isopropyl alcohol which is surgical spirit. It is denatured and should not be drunk as it is poisonous.

There are quite a lot of none denatured ethanol 70% and 95/96% ethanol on eBay UK. It is made in Bulgaria and some sellers post the link to the manufacturers website. It is meant for external usage as the website shows cutaneous and it is meant for sterilization of skin. It is for sale on ebay.com but looks like it ships from Bulgaria so it might need customs clearance. Shipping is quite expensive, especially for 4x1000ml & 6x1000 ml. See if you can find any ethanol none denatured on eBay. Some might sell it.

Some of the sellers claim it is Food grade but I seriously doubt that after reading the manufacturers website where it clearly states that it is for cutaneous (skin) usage.
https://www.ebay.com/itm/1000ml-Ethanol-Ethyl-alcohol-95-Non-Denatured-Food-Grade-Pure-Alcohol/262512501446?hash=item3d1ef6e2c6:g:QQAAAOSwvg9XfKJF

I purchased some of the stuff from Bulgaria which is sold on eBay.co.uk. The seller told me that shipment was delayed because there was a quality problem and he needed to get a replacement. What I received seems quite decent. It's clear and has only a minor smell of wheat. I have not drunk any so cannot comment on the taste. I might add some water before sipping a small amount to check the taste before I use it.

Before these sellers began selling this ethanol from Bulgaria it was quite difficult and expensive finding high strength alcohol in the UK. The best that I have found is 95% vodka which costs just over £30 for 500ml which is 5.5x the price that I paid for the ethanol that I purchased. That is no longer in stock but it was when I last looked about a week ago.

Can you not get Everclear in your State?
https://en.wikipedia.org/wiki/Everclear_(alcohol)
It looks like Luxco makes a couple of other products which are very similar to Everclear.
Last edited by BrightSideOfLife on Fri Mar 30, 2018 2:23 pm, edited 1 time in total.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#173  Post by BrightSideOfLife » Fri Mar 30, 2018 1:31 am

ISMA wrote:Dear Chris,

Why do you prefer lecithin granules than liquid lecithin?

For me it is difficult to find sunflower lecithin granules.

Thank you very.

Isma.

I have never seen sunflower lecithin granules, I have only ever seen it as powder or a really thick and difficult to use "liquid".

It depend upon where you are for availability. I purchased mine from Germany which was a lower price than in the UK. There did seem to be a shortage of Sunflower lecithin for quite some time and my previous supplier had no stock and even stock in the US was difficult to find.

Be aware that the PhosphatidylCholine content of Sunflower lecithin tends to be lower than Soya Lecithin so you would need to adjust the quantity to ensure sufficient PC.
https://shop-breinbauer.com/

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#174  Post by infinitey » Wed Apr 04, 2018 2:35 am

BrightSideOfLife wrote:Can you not get Everclear in your State?
https://en.wikipedia.org/wiki/Everclear_(alcohol)
It looks like Luxco makes a couple of other products which are very similar to Everclear.

Thank you for your reply BrightSide. Sorry for the late reply; I suffer from chronic fatigue and only have random spurts of energy to be able to do anything.

I thought the denatured aspect was to make the alcohol distasteful, not poisonous. The label said ethyl rubbing alcohol, with isopropyl rubbing alcohol being a separate product. I didn't buy either of them. I'm in California where Everclear is illegal.

I found an eBay US seller who sells medical grade 95% ethanol, so I plan to buy some of it. But I also have IBS and candida issues, and have become concerned that the alcohol will have a negative impact on me. Will the alcohol be just as effective in creating liposomes if I were to use half the recommended amount when making lipo C? I realize the author of Quality Liposomal Vitamin C says alcohol is an important ingredient.

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#175  Post by BrightSideOfLife » Thu Apr 12, 2018 9:45 pm

infinitey wrote:
BrightSideOfLife wrote:Can you not get Everclear in your State?
https://en.wikipedia.org/wiki/Everclear_(alcohol)
It looks like Luxco makes a couple of other products which are very similar to Everclear.

Thank you for your reply BrightSide. Sorry for the late reply; I suffer from chronic fatigue and only have random spurts of energy to be able to do anything.

I thought the denatured aspect was to make the alcohol distasteful, not poisonous. The label said ethyl rubbing alcohol, with isopropyl rubbing alcohol being a separate product. I didn't buy either of them. I'm in California where Everclear is illegal.

I found an eBay US seller who sells medical grade 95% ethanol, so I plan to buy some of it. But I also have IBS and candida issues, and have become concerned that the alcohol will have a negative impact on me. Will the alcohol be just as effective in creating liposomes if I were to use half the recommended amount when making lipo C? I realize the author of Quality Liposomal Vitamin C says alcohol is an important ingredient.

It's been a while since I last came into this forum, I am busy doing research and trying to work out what will work best.

IBS would most likely react to changes in what you consume due to Increased Digestive Permeability Syndrome aka Leaky Gut. It is caused by an infection which is NOT in the colon, it is in the stomach! It could be linked directly to your CFS which usually affects the right transverse colon. Being in the stomach makes it far easier to treat but they are biofilm protected and can be extremely resistant. I came across a site linked below that details how to make liposomal essential oils of which some have very strong antimicrobial effects. Quorum Sensing Inhibition does make it easier to eliminate the biofilm and Efflux Pump Inhibitors help prevent the micro-organisms from eliminating the antimicrobials.

I also suffer from CFS and find that not changing what I consume causes far less problems for me. Whenever I add anything new I suffer extreme exhaustion, otherwise things are less debilitating.

Alcohol is important for the forming of liposomes therefore I would not reduce the amount you use. It could be the difference between making an emulsion and liposomes.

http://www.eytonsearth.org/earthcures/how-to-make-liposomal-essential-oils-at-home-ultrasonic-method-tutorial-leos/

If you have not already found phoenixrising forum then here is the link http://forums.phoenixrising.me/index.php

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Re: New Method for Very High Potency Liposomal Vitamin C

Post Number:#176  Post by ekaitz » Mon Apr 16, 2018 1:36 pm

BrightSideOfLife wrote:I also suffer from CFS and find that not changing what I consume causes far less problems for me. Whenever I add anything new I suffer extreme exhaustion, otherwise things are less debilitating.


Do you know which is the root of your condition? CFS is a very vague term used for multiple things. By what I read, there are two main types, the "softer" adrenal inssuficiency which may relate to hormone depletion and imbalance, hypocortisolism, hypothyroidism.. etc, and the "harder" myalgic encephalomielitis, in which parasite infection is said to be involved and inmune system over reactive or seriously compromised.

If you suspect the first, have you got tested for thyroid, adrenal hormones, testosterone, 25OH status?

How much liposomed C do you take daily?


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