In the video I just linked to Pauling says for someone healthy already 2 grams of lysine could be enough to prevent CVD. Someone with already heard-attack or 3 bypasses, would need much more lysine. Here with preconditions he encourages to experiment with higher amounts. In other videos he mentions 5-6 grams of lysine a day with preconditions.
Again, someone with 140 kg of body-weight, with multiple bypasses simply may need much, much more than an other without bypasses and 70 kg only. Everyone has to experiment to find the doses which work for one.
Even though I weight 60 kg only, when I started Pauling Therapy 9 years ago I slowly increased the doses of vitamin C and lysine. After 1 year I reached about 6 gram for both, and at that point my intermittent-claudication symptoms greatly improved. For me a sign that 6 g lysine additional to food would be just the right dose.
Other additional conditions made me increase the vitamin C dose gradually much further. And found the most benefit that way at about 23 g for me. However, the amounts I found which would work for me might not work for another. Experiment.
bzmazu wrote:...no upper limit then? Experimenting??
The upper limit is where side-effects (gastrointestinal discomfort) overweight the health-benefits. This sweet-spot is individual and has to be found by oneself. For which Pauling gives guidelines.
Here an other seemingly contradicting guideline from Pauling in his book:
Take vitamin E every day, 400 IU, 800 IU, or 1600 IU.
But only contradicting if one completely ignores that we all have different bio-chemical individuality. Different severe preconditions, completely different weight, diet, genetics, lifestyle... etc.